https://tahtamedia.co.id/index.php/mjn/issue/feed 2026-04-02T07:34:16+00:00 Dr. Uswatun Khasanah., M.Pd.I uzwa.staimklaten@gmail.com Open Journal Systems <p><strong>Medical Journal of Nusantara</strong> <strong>(MJN) </strong>is a journal published by <strong><a href="https://tahtamedia.co.id/" target="_blank" rel="noopener">Tahta Media Group </a></strong>in collaboration with the<strong><a href="https://drive.google.com/file/d/1yQKD9nROJOFmmC0H6LZZzkuhjZb3bhJo/view?usp=sharing"> Poltekes Kemenkes Surakarta</a> E-ISSN : <a href="https://issn.perpusnas.go.id/terbit/detail/20220814532031643">2964-0598</a>, P-ISSN <a href="https://issn.perpusnas.go.id/terbit/detail/20221210540996731">2963-0150 </a></strong>is a scientific journal that publishes research articles, case reports, case reports, literature reviews (reviews), and other topics relevant to the field of medicine and health. <strong>Medical Journal of Nusantara</strong> <strong>(MJN)</strong> is published three times a year, namely every <strong><em>March, August, December</em></strong></p> <p><strong>Published areas of knowledge include:</strong></p> <ul> <li>Nursing</li> <li>Pharmacy</li> <li>Physiotherapy</li> <li>Health Technology</li> <li>Nutrition And Nutrition</li> <li>Public Health</li> <li>Obstetrics</li> <li>Education And Health Promotion</li> <li>Hospital Administration and Management</li> <li>Health Law and Ethics</li> <li>Occupational Health and Safety</li> <li>Maternal and Child Health</li> <li>Mental Health</li> <li>Medical Education</li> </ul> <p>Submit your manuscripts today! through our online system (If you reached any problems in your papers submission, please contact us at email: <a href="mailto:admin@tahtamedia.co.id">admin@tahtamedia.co.id</a> Download <strong>Medical Journal of Nusantara</strong> <strong>(MJN)</strong> Guide of Authors for writing and style in here.</p> <p> </p> <p> </p> https://tahtamedia.co.id/index.php/mjn/article/view/1950 2026-04-02T07:34:16+00:00 Yulia Ratna Dewi yuliaratnadewi@poltekindonusa.ac.id Arum Kusuma Putri kusumaarum@poltekindonusa.ac.id Mutia Azahra zahramutia497@gmail.com

<p data-start="220" data-end="611"><strong data-start="220" data-end="235">Background:</strong> Diabetic foot ulcers (DFUs) are among the most severe complications of diabetes mellitus, contributing significantly to morbidity, prolonged hospitalization, and lower-extremity amputations. Infection plays a critical role in the progression of DFUs, with diverse bacterial involvement and increasing antimicrobial resistance posing major challenges to effective treatment.</p> <p data-start="613" data-end="779"><strong data-start="613" data-end="627">Objective:</strong> This study aimed to review and synthesize current evidence on bacterial identification and antimicrobial resistance patterns in diabetic foot ulcers.</p> <p data-start="781" data-end="1224"><strong data-start="781" data-end="793">Methods:</strong> A semi-systematic literature review was conducted using electronic databases, including PubMed, Scopus, ScienceDirect, and Google Scholar. The study selection followed PRISMA guidelines. A total of 130 articles were initially identified, of which 30 studies met the inclusion criteria after screening and eligibility assessment. Data were extracted and analyzed using a qualitative descriptive approach with narrative synthesis.</p> <p data-start="1226" data-end="1979"><strong data-start="1226" data-end="1238">Results:</strong> The findings revealed that diabetic foot infections are predominantly polymicrobial, with a higher prevalence of Gram-negative bacteria compared to Gram-positive organisms. The most frequently identified pathogens included <em data-start="1462" data-end="1485">Staphylococcus aureus</em>, <em data-start="1487" data-end="1505">Escherichia coli</em>, <em data-start="1507" data-end="1530">Klebsiella pneumoniae</em>, and <em data-start="1536" data-end="1560">Pseudomonas aeruginosa</em>. A significant proportion of isolates exhibited resistance to commonly used antibiotics, particularly penicillin, amoxicillin, and trimethoprim-sulfamethoxazole. Gram-negative bacteria demonstrated more complex resistance mechanisms, including extended-spectrum beta-lactamase (ESBL) and carbapenemase production. Multidrug-resistant (MDR) organisms were commonly reported, further complicating treatment strategies.</p> <p data-start="1981" data-end="2425"><strong data-start="1981" data-end="1996">Conclusion:</strong> Diabetic foot infections represent complex polymicrobial conditions with a predominance of Gram-negative bacteria and a growing burden of antimicrobial resistance. Accurate bacterial identification and antibiotic susceptibility testing are essential to guide targeted therapy and improve clinical outcomes. Continuous surveillance and rational antibiotic use are necessary to prevent the further spread of resistant pathogens.</p>

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